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An eGFR just below 60 typically indicates the presence of early-stage CKD and is also associated with a significantly increased risk of cardiovascular and any-cause mortality, kidney failure, acute kidney injury, or the progression of CKD

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Furderer S, Wenda K, Thiem N, Hachenberger R, Eysel P

Luminescence was sequentially measured using a Varioskan Flash (Thermo Fisher Scientific Inc., MA, USA)

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This may effectively prevent brain edema resulting from experimental CI in rats (Zhang et al., 2006