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Early enteral administration of a formula (Impact) supplemented with arginine, nucleotides, and fish oil in intensive care unit patients: results of a multicenter, prospective, randomized, clinical trial

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FOXA1 can promote the expression of E-cadherin, while BACH1 inhibits the expression of FOXA1 and genes critical for epithelial cell adhesion, including claudin3 and claudin4, thus promoting the EMT

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The first is starting at a dose lower than the labeled starting amount