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Tirzepatide (Mounjaro, Zepbound): This medication works on both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors , meaning it has a dual action that may lead to even greater weight loss results compared to Semaglutide

Discussing all medications, supplements, herbs, and vitamins you take with a doctor or pharmacist is important to reduce the risk of drug interactions.

One possibility is that people might have genetic mutations in their GLP-1 receptors, that just make them less responsive to these drugs

an average weight loss of 13.7% of participants taking semaglutide

Semaglutide with glycine is a compounded medication that combines the GLP-1 receptor agonist semaglutide with the amino acid glycine

"Some people may need to do that (stay on medications), and that's totally valid