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For example, paramagnetic metals can participate in ROS production through Fenton or Haber-Weiss reactions, which, at elevated levels, may cause oxidative damage to proteins, nucleic acids, and lipids, leading to cell death (Hajipour Verdom et al., 2018

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Phase III, multicenter, double-blind, randomized study of letrozole, an aromatase inhibitor, for advanced breast cancer versus megestrol acetate