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They are compatible with techniques based on transdermal delivery systems

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59 Among pivotal patients with BBS who were greater than or equal to 18 years of age, | || || || || | of patients achieved a clinically meaningful ( 5%) reduction in body weight and | || || || achieved a greater than or equal to 10% reduction in body weight after 52 weeks of setmelanotide treatment

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The initial dose of retatrutide is important because it helps to minimize the risk of side effects

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Zhu H, Zhang Y, Shi Z, Lu D, Li T, Ding Y, et al

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Cell 138 , 257270 (2009)

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