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Ong JP, Aggarwal A, Krieger D, Easley KA, Karafa MT, van Lente F, et al

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Copper is only required in trace amounts by the body, and too much copper buildup could theoretically cause nausea, abdominal pain, tiredness, liver damage, and neurological effects

Taken together, in addition to some common benefits for CV systems, it is likely that GLP-1RAs improved overall CV outcomes mainly by reduction in atherosclerotic events, whereas SGLT2 inhibitors improved CV outcomes mainly via prevention of HF-related outcomes (Fig

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