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Importantly, these pseudo leukotrienes activated key inflammatory pathways (ERK and Akt) in bronchial epithelial cells, and this activity was blocked by CysLT receptor antagonists such as Montelukast and Zafirlukast

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This observation conclusively suggested that GPx might not be directly involved in the protection of cells from radiation-induced cell death

These results proved that NAC were stable in placebo and standard solutions prepared as described in the experimental section, indicating preparation procedure for placebo sample and standard solution was suitable for intended application of the method