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Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure

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We previously established quantitative procedures to analyze metabolites of human whole blood, plasma, and RBCs (red blood cells) by LC-MS (liquid chromatography-mass spectrometry) 6,7 based on our experience in developing metabolomic methods for fission yeast cells under various nutritional and genetic pertubations 8,9,10,11