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Furthermore, PS1V97L transgenic mice exhibited increased inflammatory cytokines including IL-1 and TNF, which were attenuated by sulforaphane supplementation (Hou et al., 2018)

In this regard, topical triple combination therapy containing hydroquinone 4%, tretinoin 0.05%, and fluocinolone 0.01% have received the Food and Drug Administration (FDA) approval in melasma management

Following the experiment, the femur bones underwent further analysis with mid-diaphyseal peripheral quantitative computed tomography (pQCT) scans

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Experiments were carried out by researchers using Tet-mev-1 mice, which have mutations in their mitochondrial complex II and an excessive production of ROS