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However, the gastrointestinal adverse effects of Wegovy, particularly nausea, vomiting, and diarrhoea, can occasionally lead to dehydration, which might cause orthostatic hypotension or compensatory tachycardia in susceptible individuals

Although several methods have been found to promote the replication of beta cells in animal models or cell lines, it is still challenging to promote the effective proliferation of beta cells in humans

7 Prevalence and duration of gastrointestinal events by severity

In particular, exposure to lead results in a significant down-regulation of astrocytic glutamate transporters 387 and in cell swelling possibly because of increased water transport through AQP4 channels

Heart 17 (1), 42

and Mishra, S., 2023