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Initial investigations may include complete blood count, metabolic panel, thyroid function tests, hemoglobin A1c, ESR/CRP, HIV testing, and urinalysis when clinically indicated

Physical dependence is a state that develops as a result of physiological adaptation in response to repeated drug use, manifested by withdrawal signs and symptoms after abrupt discontinuation or a significant dose reduction of a drug

doi: 10.1016/S0140-6736(17)31585-4 75 ZhangLZhangLLiLHlscherC

Xiao-Yun X, Zhao-Hui M, Ke C, Hong-Hui H, Yan-Hong X

for dulaglutide (Trulicity), within 3 days

Active ingredient: tirzepatide Inactive ingredients (single-dose pens and vials): Sodium chloride Sodium phosphate dibasic heptahydrate Water for injection Hydrochloric acid and/or sodium hydroxide (added to adjust pH) Additional inactive ingredients (KwikPen and multi-dose vial only): Benzyl alcohol Glycerin Phenol What strengths are Zepbound pens