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Here's an angle that often gets overlooked: copper is a required cofactor for tyrosinase , the enzyme that produces melanin

Schuhmacher R, Sulyok M, Krska R (2008) Recent developments in the application of liquid chromatographytandem mass spectrometry for the determination of organic residues and contaminants

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Excess Fe 2+ is exported via ferroportin (FPN) to maintain intracellular iron homeostasis (Wang et al., 2025d