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doi: 10.4161/cbt.5.7.2967 76 DekervelJBulleAWindmoldersPLambrechtsDVan CutsemEVerslypeCet al

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c f , Inactive analog KL7 (40, 100 M) and weak analog KL2 (100 M) showed minimal to no effect on ROS/RNS levels in infected ( c , d ) and uninfected ( e,f ) macrophages after 4 h ( c , e ) and 8 h ( d,f ) treatment

Schaub, J., Van Hoof, F

This mechanism raises the critical discontinuation question - does stopping GHK-Cu immediately halt enhanced collagen production returning synthesis rates to pre-treatment baseline, or does the improved dermal environment created during treatment continue supporting elevated collagen production through positive feedback mechanisms where better matrix structure itself promotes ongoing synthesis even without continuous peptide stimulation