At low weekly doses, the 28-day reconstituted-use window is the practical cap reconstitute in halves if dosing slower than 2.5 mg/week
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Malabsorption of vitamin B12 may occur with neomycin, colchicine, para-aminosalicylic acid, or prolonged alcohol intake
Other conditions may require spacing of 10 weeks
[1] [4] When B12 is deficient, myelin production is impaired, leading to demyelinationthe breakdown of this protective sheathwhich results in abnormal nerve signalling perceived as pain, tingling, or numbness
These early signals suggest the peptide is active even before major healing becomes apparent