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GLP-1 receptor agonists work by mimicking the effects of 1, 2, or 3 naturally produced digestive hormones, including glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide (GIP)

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The gastrointestinal tract and glucose tolerance

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Semaglutide, marketed as Ozempic for diabetes and Wegovy for obesity, has emerged as the commercial powerhouse, with the oral version launching in January 2026 following December 2025 FDA approval [3]