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Beyond anorexia, the compression exerted by triglyceride-infilled hepatocytes on the bile ducts results in severe cholestasis, which reduces the enterohepatic circulation of cobalamin

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PEPITEM-derived tripeptides modulate adaptive immune responses

Cartilage & Joint Research Kwon and Park, Annals of Clinical and Laboratory Science (2015) Kwon and Park investigated the chondroprotective effects of intra-articular AOD-9604 administration in a rabbit model of osteoarthritis, with and without co-administration of hyaluronic acid

Gradual dose escalation over 16-20 weeks greatly reduced the incidence of nausea and vomiting compared to faster titration, while still achieving excellent weight loss outcomes