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Those numbers mean most patients will not develop persistent arrhythmias, but if palpitations are accompanied by chest pain, fainting, or breathlessness, treat them as urgent

Udelson D et al

If you have a known heart condition particularly arrhythmia, heart failure, or resting tachycardia flag this specifically when discussing retatrutide with a cardiologist or prescribing physician before treatment begins

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MK-677 is generally well tolerated but can increase water retention, appetite, and blood sugar in some patients

GLP-1RAs may also influence growth hormone (GH) secretion, which is integral to maintaining lean mass via IGF-1-mediated protein synthesis