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This therapeutic effect was mechanistically linked to reductions in pro-inflammatory cytokines (TNF-, IL-1), enhancement of antioxidant defenses (e.g., increased superoxide dismutase activity), suppression of apoptosis via caspase-3 inhibition, and modulation of NF-B pathwayscollectively yielding neuroprotection and symptomatic relief ( Curcumin shows therapeutic potential for managing peripheral neuropathic pain through multiple mechanisms (Hasriadi et al., 2021)

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Before we can draw a comparison, we need to establish a solid foundation

In the study, 11 healthy and athletic men and women were examined in a double-blind, placebo-controlled crossover trial evaluation

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