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IGF-1 is used to describe the pharmaceutical agent

One study in diet-induced obese mice found that an NNMT inhibitor combined with a calorie-restricted diet was associated with shifts in gut bacterial populations, suggesting metabolic intervention can have knock-on effects on gut composition

Same FDA crackdown applies

The headline numbers from the phase 2 obesity trial were striking: the highest dose group averaged 24.2% body weight reduction at 48 weeks, far ahead of what any single-mechanism drug had managed

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The study protocol was approved by the ethics committee of Korea University Hospital, and the study was conducted in accordance with the guidelines of the Helsinki Declaration