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Promising drug categories include: cholesterol-lowering drugs (e.g., aramchol), 104 FXR agonists (e.g., obeticholic acid, 105 tropifexor), 106 PPAR agonists [e.g., elafibranor (PPAR /), 107 saroglitazar (PPAR /), 108 pemafibrate (PPAR) 109 ], Thyroid hormone receptor agonists (e.g., resmetirom), 110 and FGF21 analog (e.g., pegbelfermin)

However, studies do show that medications affecting the digestive system can potentially exacerbate GERD symptoms