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doi:10.1016/j.jtos.2017.05.003 3

Their conclusion: sleep improvement under DSIP treatment is of little clinical significance. [11] Bes and colleagues in Amsterdam ran a double-blind matched-pairs parallel-groups design in 16 chronic insomniacs and found the statistically significant effects were weak and in part could be due to an incidental change in the placebo group, with subjective sleep quality unchanged

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Retatrutide produces greater weight loss at every comparable timepoint, despite using a lower maximum dose (12 mg versus 15 mg)

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