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neurological effects, such as headaches, a sense of restlessness, or trouble sleeping

Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study

Less sustainable More people are becoming familiar with the term Ozempic Rebound, where people regain weight after they stop their semaglutide regimen

Anecdotally, many patients report a 30 to 50% reduction in peak nausea severity

Without semaglutide, participants relying solely on lifestyle changes shed approximately 2.4% of their weight in the same period

The SELECT trial took it further