Metabolism: Clinical and Experimental , 50 (12), 14291434
In cancer cells, GLS supports the production of glutamate, which is vital for the synthesis of GSH, a major antioxidant that scavenges ROS, triggering oxidative stress and eventually leading to apoptosis (211)
Real research requires transparent methodology , reproducible results, independent verification, and regulatory oversight
mTOR signaling pathway mTOR, a member of the PI3K-related kinase family, is the core component of two structurally and functionally distinct protein complexes, mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2)
FBXL5 regulates IRP2 stability in iron homeostasis via an oxygen-responsive [2Fe2S] cluster
Another Harvard-led study found a 29% increase in coronary heart disease risk for each 0.5-point increase in HbA1c above 5.0%. Those numbers matter even when results technically fall within the normal range