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M.AsiriM
NAA is synthesized in neurons from aspartate and acetyl-CoA within the matrix of nerve cell mitochondria via the action of N -acetylaspartate synthetase which is encoded by the NAT8L (N-acetyltransferase 8 like) gene
these include the processing of the amyloid precursor protein, the aggregation of the amyloid beta peptide and the tau, impaired autophagy, and neuroinflammation that have therapeutic effects in AD (21, 5053)
This suggests that Cd has a direct effect on the acceleration of lipolysis, increasing the degradation of stored lipids and suppressing adipogenic gene expression [83]