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The reason for this is that there is skewing of X chromosome inactivation such that females with one mutant PDHA1 gene appear to have the X chromosome harboring the wild-type PDHA1 gene inactivated at a higher rate than predicted based upon the normal random X-inactivation process

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increased cholesterol, triglyceride, or blood sugar levels

a , Response of the community periphery (left panel) and interior (right panel) to tetracycline treatment respectively

Blood 130 , 245257 (2017)

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