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N Engl J Med 385(16):14511461 Solomon SD, McMurray JJV, Claggett B, de Boer RA, DeMets D, Hernandez AF et al (2022) Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction
doi: 10.1002/jnr.22565 167 McGovernSFHunterKHolscherC
However, Epithalon remains investigational with no FDA approval, most research conducted in Russia with limited Western replication, long-term human safety data sparse, optimal dosing protocols still debated, and mechanisms not fully understood
G.RaikosN.TheodoridisG
NAC also demonstrates benefits beyond just glutathione production, including direct free radical scavenging and support for healthy inflammatory responses
Glutathione also protects mitochondrial membranes from oxidative damage
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