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Phase 3 results showed approximately 15-17% body weight reduction over 48 weeks, positioning it competitively with tirzepatide

2 ottobre 2018 [citato 2 aprile 2023];169(7):46773

Mol Pharmacol (1999) 56:23542

An FLI value below 30 (negative likelihood ratio up to 0.2) suggests excluding the presence of liver steatosis, whereas an FLI equal to or higher than 60 (positive likelihood ratio starting from 4.3) was considered indicative of liver steatosis ( The FIB4 (Fibrosis-4) index for liver fibrosis was calculated as follows: FIB-4 = (AST x Age)/(Platelet count x (ALT))

In placebo-controlled trials, severe GI reactions were reported in 4.1% of Wegovy-treated patients compared to 0.9% of placebo-treated patients

10.1016/j.jacc.2021.12.011 31 HermansenK.BkdalT