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10.1016/j.biopha.2020.110735 33 HeldtH.-W.PiechullaB

Freezethaw cycles may: Affect molecular stability Increase aggregation risk in some formulations Reduce overall consistency of the solution Storage at 28C is typically preferred unless otherwise validated

DOI: 10.1016/j.ab.2010.06.034 41

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These are algorithms that estimate the age of the body through DNA methylation, chemical marks that attach to the genome over a lifetime and shift their pattern