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Maturitas 126, 2833

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GLP-1 medications are not approved as cancer prevention or cancer treatment

Gene variants on genes such as MTHFR encoding methylenetetrahydrofolate reductase, MTR encoding methionine synthase, MTRR encoding methionine synthase reductase and CBS encoding cystathionine-B synthase in the methylation pathway can lead to a decreased ability to create sufficient methyl donor (SAMe) and may lead to disruptions in the SAMe:SAH ratio, thus altering methylation capacity and epigenetic regulation

Results lifespan: Outcomes seen within several months

Its multi-receptor activity gives it a broader research profile than more selective melanocortin agonists