2 A 2020 meta-analysis pooled data from 12 randomised-controlled trials (RCTs) looking at the effect of NAC on biomarkers of oxidative stress, and found a significant decrease in malondialdehyde (a marker of oxidative stress) 7
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Over weeks or months, this amount is increased in a step-wise method (often called titration) to help your body respond better while keeping side effects to a minimum
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However, there is an interdependent relationship in which the NADPH pool is simultaneously supported and used by various pathways in cells
