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Experimental evidence demonstrates that microbiota-derived tryptophan metabolites act as pregnane X receptor agonists, inducing CYP3A4 and multidrug resistance protein 1 (MDR1) expression (Morgan et al., 2018)

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FTIR spectra were recorded from 750 cm 1 to 4000 cm 1 with a spectral resolution of 4 cm 1

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