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doi: 10.1084/jem.20050749 416 TownsendR.DietzA.HaleC.AkhtarS.KowalskiD.LademacherC.et al

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimers disease mouse models

Cani PD, Possemiers S, Van de Wiele T, Guiot Y, Everard A, Rottier O, et al

The improvement in pharmacokinetics helped prevent the negative gastrointestinal side effects typical of GLP- 1-based selective agonists by reducing maximum drug exposure and reducing reliance on GLP- 1-mediated pharmacology

A reduction in precision is not necessarily a loss of real information, as rounding errors that occur are relative to a reference that itself comes with uncertainty

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