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(October 2025)

Key Takeaways Nausea is one of the most common side effects of GLP-1 medications and is usually most noticeable when starting treatment or increasing your dose

As reported previously, we confirm autoradiography and immunohistochemistry data 2, 24 showing that human pancreatic acini do express GLP1R, although in much lower density than the insulin-producing cells

Seek emergency medical care immediately if you experience a rash, itching, swelling of the face or throat, difficulty breathing, or a rapid heartbeat

doi: 10.1016/j.tips.2022.11.001

By contrast, administration of serotonin receptor 2 antagonist (ketanserin) abolished the impact of serotonin to induce hypoglycemia, in concert with decreased insulin and GLP-1 secretion