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Dosing Protocol A suggested titration approach based on common reference doses for GHK-Cu

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all clinical signs will worsen with time and cardiovascular complications, including congestive heart failure, may develop

The modified peptide was deprotected/cleaved and macrocyclized as described above, followed by RP-HPLC purification and in vacuo lyophilization

doi: 10.1002/1531-8249(199911)46:5 3.0.CO;2-8 29 BourassaM

injection of 50 g/100 l of exendin-[939] (Ex9) (Bachem Bioscience, Torrance, CA, USA) or saline (NaCl 154 mmol/l) 45 min before an oral glucose load (200 l of 20% wt/vol