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Also high-valent chromium(VI) is able to generate reactive ROS during its conversion to the stable Cr 3+ oxidation state [13] and this mechanism has been associated to the recognized carcinogenic activity of chromate salts [14]

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Mol Cell 31:143151 Zhang M, Huang N, Yang X, Luo J, Yan S, Xiao F, Chen W, Gao X, Zhao K, Zhou H et al (2018a) A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis