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10.3390/nu17081303 [DOI] [PMC free article] [PubMed] [Google Scholar] 27

Cases 11 (20), 47404751

Specific Mechanistic Effects Laboratory studies have documented cagrilintide-associated effects, including: Satiety-promoting signaling linked to reduced food intake Delayed gastric emptying , reflected by slowed gastric transit Reduced post-prandial glucagon secretion Enhanced regulation of energy balance Modulation of hypothalamic appetite centers and feeding-behavior circuits These effects arise from activation of the amylin and calcitonin receptors in appetite-regulating brain regions and peripheral metabolic tissues

All animal care and experimental use were performed according to protocols approved by the CAM-SU Animal Care and Use Committee (ZJ-2024-01)

doi:10.1097/01.jom.0000177336.21147.9f