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Lectures: Bayer, Lilly, AstraZeneca, Novo Nordisk, Sanofi, Abbott, Merck, Novartis

A study in The New England Journal of Medicine found that 59 percent of patients with NASH (non-alcoholic steatohepatitis) who took a high dose of semaglutide for 72 weeks saw improvement without worsening of fibrosis (or scarring)

Clinical trials show GLP-1 agonists generally produce weight reductions of 5-15% depending on baseline metabolism, medication adherence, and concurrent lifestyle changes

Mechanistically, both improve insulin sensitivity and body composition

These include local irritation or redness at injection sites, mild headaches or dizziness, and occasional fatigue or nausea