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Notably, the incidence of skin rashes is comparable to that observed with allopurinol

Biometals 31(5):845858

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For Epithalon, continuous use is not typically recommended

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Leukocyte-binding to adhesion molecules on endothelial cells is an early event in atherogenesis, and the upregulation of leukocyte binding in GPx1-deficient cells is consistent with enhanced lesion development in atherosclerotic-susceptible mice