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Weight regain is common after discontinuation

After the two-month break, patients who continue into a second cycle return directly to the month-three maintenance dose rather than restarting the ramp from month one

(5) Yanqing Li, Chi Zhang, Haicheng Cheng, LinYan Lv, Xinning Zhu, Menghui Ma, Zhenhan Xu, Junxian He, Yun Xie, Xing Yang, Xiaoyan Liang, Chunhua Deng, Guihua Liu, FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells, Experimental Gerontology, Volume 195, 2024, 112522

It is not FDA approval as a finished drug product

What is CagriSema

doi: 10.1046/j.1523-1747.2002.19520.x 47 YoshiokaMSawadaYSaito-SasakiNYoshiokaHHamaKOmotoDet al