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OXPHOS perturbation-induced hemocyte activation is not dependent on ROS The disruption of OXPHOS, especially complexes I and III, leads to an increased electron escape, creating increased amounts of reactive oxygen species (ROS) (reviewed in [38])

Furthermore, GLP-1 plays a protective role in cardiac microvasculature in diabetes by preventing apoptosis, oxidative stress, and microvascular dysfunction

doi: 10.2147/CPAA.S374741 137 MahapatraMKKaruppasamyMSahooBM

Why or why not

Regular review of weight loss progress, typically every three months, allows assessment of treatment response and consideration of whether continuation is appropriate according to NICE TA875, which recommends discontinuation if less than 5% weight loss is achieved after six months at the maintenance dose

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