The Cas9/sgRNA ribonucleoprotein complex, while the most responsive mode of action, has a low off-target rate and low toxicity, but the large size of the complex complicates delivery
doi: 10.1111/cpr.12330 37
Contraindications: Do not take if you have an allergy or hypersensitivity to acetaminophen or any component of formulation, or a history of severe hepatic impairment
Many mucus-targeting therapeutics act by rehydrating and cleaving mucins
But I think its still an open question about their effect on cancer. These drugs include semaglutide (sold under the brand names Ozempic, Wegovy and Rybelsus) and tirzepatide (brand names Mounjaro and Zepbound)
GIP (glucose-dependent insulinotropic polypeptide) has been identified in reproductive tissues, and GIP receptor activation may contribute to the hormonal benefits observed with tirzepatide