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A decrease in cardiac output leads to the secretion of Renin, which then catalyses the formation of angiotensin I (Ang I) from its precursor Angiotensinogen

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Another antioxidant enzyme, paraoxonase 1 (PON-1), is associated with high-density lipoprotein (HDL), detoxifies lipid peroxide (LOOH) and prevents low-density lipoprotein oxidation, thereby protecting tissues from oxidative damage (26)

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