Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG
Metformins effect on first-year weight gain: A follow-up study
Pre-restart assessment should include: Review of your medical history and any changes during the treatment break Evaluation of renal function, particularly if you have existing kidney disease Review of concurrent medications, especially other diabetes treatments that may increase hypoglycaemia risk Discussion of your previous experience with Mounjaro, including efficacy and tolerability Assessment of pregnancy status and contraception needs (tirzepatide is not recommended during pregnancy) Consideration of thyroid health (patients with a personal or family history of thyroid cancer should discuss this with their clinician) For weight management indications , NICE guidance (NG219) provides a framework for specialist weight management services
Whilst pancreatitis remains a recognised potential side effect, the absolute risk is small, and people with type 2 diabetes already have an elevated baseline risk of developing this condition
Typically, these side effects occur as the dosage increases and then taper off
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