It can reduce the risk of major cardiovascular events such as heart attacks and strokes in people with type 2 diabetes who have existing heart disease
Understanding what is in development provides context for future choices

Sample High-Protein Day (135g) Here's what 135g of protein looks like in GLP-1-friendly portions: Breakfast (8 AM) - 35g protein 2 scrambled eggs with spinach (12g) 1 chicken sausage link (12g) cup cottage cheese with berries (14g) ~325 calories Mid-Morning Snack (11 AM) - 25g protein Greek yogurt protein smoothie: 1 cup nonfat Greek yogurt (20g) scoop protein powder (10g) Small banana Ice ~250 calories Lunch (2 PM) - 38g protein 4 oz grilled chicken breast (31g) Mixed greens with cherry tomatoes 2 tbsp balsamic vinegar Small sweet potato (3g) Steamed broccoli (4g) ~375 calories Afternoon Snack (5 PM) - 12g protein 2 hard-boiled eggs (12g) Baby carrots ~150 calories Dinner (7 PM) - 37g protein 5 oz baked salmon (35g) Roasted Brussels sprouts (3g) Cauliflower rice Lemon and herbs ~400 calories Evening Snack (Optional, 9 PM) - 15g protein cup low-fat cottage cheese (14g) Sliced cucumber ~90 calories Daily Total: Protein: 137g Calories: ~1,500 Meals: 4 main + 2 snacks Average portion size: Small, GLP-1-friendly Notice: Small, frequent meals

When the energy charge is low, CoASH is not acetylated, therefore, pyruvate carboxylase is inactive, and pyruvate is preferentially oxidized to acetyl-CoA via the PDHc
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That translated to an average weight loss of about 70.3 pounds, and more than 45% of participants on the 12 mg dose lost at least 30% of their body weight