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Safety: What is and is not known Animal safety data A 2020 preclinical safety evaluation by Xu and colleagues in Regulatory Toxicology and Pharmacology examined BPC-157 across multiple species mice, rats, rabbits, and dogs and reported no serious toxicity, no genotoxicity, and no embryotoxicity at doses evaluated

Aging and Longevity Research : Examined in bovine, porcine, and murine models for offsetting cellular aging, reducing inflammation, and mitigating conditions such as muscle atrophy or neurodegeneration

Int J Colorectal Dis

The minor benefits of sublingual administration do not justify the typically higher cost

Severe reactions like the one documented in published case reports can take up to a month to fully resolve, though these are uncommon

BioMetals 2006, 19, 6170