Currently, there are 9 GLP-1RAs approved by the FDA, widely used for the treatment of type 2 diabetes
The main concerns with GLP-1 agonist drugs include: GI side effects (nausea, diarrhea, vomiting, constipation, abdominal pain) High out-of-pocket cost for those who do not quality under insurance Risk of inadequate nutrition (reduced intake + insufficient nutrition counseling) Significant loss of muscle mass & bone density High discontinuation rates (with lost weight regained) Limited public & clinician knowledge on importance/implementation of nutrition and lifestyle changes Side Effects and Costs of GLP-1 Medications The use of GLP-1 drugs has been associated with numerous side effects, ranging from mild to severe
[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Thorens B
In most cases, weekly injections are sufficient
Cultivating a support network is useful, be that a gym partner, a trainer, or a virtual community
As GLP-1 is released, it has multiple actions at once: it delays gastric emptying, makes your brain feel full and satisfied with the food consumed, and signals the pancreas to secrete insulin