4 Interplay between mitochondrial dysfunction and fatty acid metabolic disturbances in the failing heart Mitochondrial dysfunction and FAO disorders reinforce each other in the failing heart: ETC defects and m loss suppress FAO, while dysregulated FAO promotes oxidative stress, lipotoxicity, and structural damage, further compromising mitochondrial function
Neurology 93 , e445e457 (2019)
Of note, GSTO1 was identified as one of the cellular targets of locostatin, an oxazolidinone-based cell migration inhibitor, although its role in cell migration has not been well characterized 42
Preclinical evaluation of BPC-157 and TB-500 in rodent models of soft-tissue, musculoskeletal, and gastrointestinal-mucosal repair
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