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4 The proposed mechanism involves both direct neuroprotective effects (via eNOS-NO pathway preservation of vascular supply to injured nerve) and indirect effects via modulation of the inflammatory microenvironment at the injury site

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In humans, the administration of high doses of VC intravenously for 48 h (50 mg/kg every 6 h) has been shown to reduce the plasma syndecan-1 concentration (129)

Choosing between these two can be confusing without understanding how they work, their effects, and what suits your goals best

New formulations, regulatory evaluations, and continuous clinical trials will probably shape future peptide treatment

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