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Importantly: Neither peptide is FDA-approved for human use There are no large-scale human clinical trials validating safety or efficacy Quality and purity are often uncertain when purchased through underground or non-medical sources Despite this, BPC-157 and TB-500 are popular in bodybuilding, CrossFit, and athletic recovery spaces because of claims around faster healing and reduced downtime from injuries

Neurosci Lett 178:6365 Robinson MB, Anegawa NJ, Gorry E, Qureshi IA, Coyle JT, Lucki I, Batshaw ML (1992) Brain serotonin 2 and serotonin 1A receptors are altered in the congenitally hyperammonemic sparse fur mouse

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[3] There is evidence that valproic acid may cause premature growth plate ossification in children and adolescents, resulting in decreased height

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10.1038/5030 Nat