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Notably, the Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) trial, the first dedicated kidney outcome trial evaluating canagliflozin in people with type 2 diabetes mellitus and CKD, demonstrated a substantial reduction in the risk of kidney events [46]

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GIP influences how the body handles nutrients and appears to contribute to tolerability

But as soon as they stop it, that weight returns because it's the same thing

Trizepatide, or Mounjaro, is another GLP-1 receptor agonist drug used to treat T2DM